| Division 2 |
Wigan Knights A Team Fixtures| Day | Date | Team |
| Team | | Monday | 20th Sept 10 | Winwick A | v | Wigan Knights A | | Thursday | 28th Oct 10 | Wigan Knights A | v | St Helens B | | Monday | 8th Nov 10 | Penketh A | v | Wigan Knights A | | Thursday | 25th Nov 10 | Wigan Knights A | v | Ormskirk A | | Monday | 6th Dec 10 | Northwich B | v | Wigan Knights A | | Thursday | 6th Jan 11 | Wigan Knights A | v | Atherton B | | Thursday | 20th Jan 11 | Wigan Knights A | v | Winwick A | | Wednesday | 9th Feb 11 | St Helens B | v | Wigan Knights A | | Thursday | 17th Feb 11 | Wigan Knights A | v | Penketh A | | Thursday | 3rd Mar 11 | Ormskirk A | v | Wigan Knights A | | Thursday | 17th Mar 11 | Wigan Knights A | v | Northwich B | | Monday | 28th Mar 11 | Atherton B | v | Wigan Knights A |
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| Division 3 |
Wigan Knights B Team Fixtures| Day | Date | Team |
| Team | | Thursday | 16th Sept 10 | Wigan Knights B | v | Runcorn | | Monday | 11th Oct 10 | Widnes B | v | Wigan Knights B | | Thursday | 21st Oct 10 | Ormskirk B | v | Wigan Knights B | | Thursday | 18th Nov 10 | Wigan Knights B | v | Culcheth B | | Wednesday | 1st Dec 10 | Padgate B | v | Wigan Knights B | | Thursday | 9th Dec 10 | Wigan Knights B | v | Ormskirk B | | Tuesday | 4th Jan 11 | Runcorn | v | Wigan Knights B | | Thursday | 27th Jan 11 | Wigan Knights B | v | Widnes B | | Wednesday | 9th Mar 11 | Culcheth B | v | Wigan Knights B | | Thursday | 24th Mar 11 | Wigan Knights B | v | Padgate B |
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